Shiraz Genetic + Health Test Results + Traits + COI Information

Full Genetic Result of Shiraz is shared here. This page gets updated as we get more information and perform new tests.

Genetic Tests

Cardiology - Dilated Cardiomyopathy PDK4 (DCM 1)

NN Clear

Cardiology - Dilated Cardiomyopathy 2 (DCM 2)

NN Clear

Deafness and Vestibular Syndrome of Dobermans (DVDob, DINGS)

GG Clear

Holter Results

will publish Q4 2019

Von Willebrand Disease Type 1 (VWF)

GA Career    ( only one copy – safe to breed with a clear stud )
Shiraz has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease.

Degenerative Myelopathy
(SOD1A)

GG Clear

MATERNAL HAPLOTYPE

HAPLOGROUP: A1a

HAPLOTYPE: A381

PATERNAL HAPLOTYPE

HAPLOGROUP: A1b

HAPLOTYPE: Ha.13

DIET - FOOD

Purina One Lamb + Some Meat
+ FRESH BROWN RICE made with  COCONUT OIL + SALMON OIL +  1000mg  daily TAURINE Suppliment

 

Routine Checkups

Healthy

Full Genetic Results

CLINICAL

MDR1 Drug Sensitivity (MDR1)

NN Clear

BLOOD

P2Y12 Receptor Platelet Disorder (P2RY12)

NN Clear

Factor IX Deficiency, Hemophilia B

(F9 Exon 7, Terrier Variant)

GY Clear

Factor VII Deficiency

(F7 Exon 5)

GG Clear

Factor VIII Deficiency, Hemophilia A (F8 Exon 10, Boxer Variant)

Clear

Factor VIII Deficiency, Hemophilia A (F8 Exon 11, Shepherd Variant 1)

Clear

Factor VIII Deficiency, Hemophilia A (F8 Exon 1, Shepherd Variant 2)

Clear

Thrombopathia (RASGRP2 Exon 5, Basset Hound Variant)

Clear

Thrombopathia (RASGRP2 Exon 8)

Clear

Thrombopathia (RASGRP2 Exon 5, American Eskimo Dog Variant)

Clear

Von Willebrand Disease Type II (VWF Exon 28)

Clear

Von Willebrand Disease Type III (VWF Exon 4)

Clear

Von Willebrand Disease Type I (VWF)

Clear

Canine Leukocyte Adhesion Deficiency Type III (LAD3) (FERMT3)

Clear

Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)

Clear

Canine Elliptocytosis (SPTB Exon 30)

Clear

Cyclic Neutropenia, Gray Collie Syndrome (AP3B1 Exon 20)

Clear

Glanzmann’s Thrombasthenia Type I (ITGA2B Exon 12)

Clear

May-Hegglin Anomaly (MYH9)

Clear

Prekallikrein Deficiency (KLKB1 Exon 8)

Clear

Pyruvate Kinase Deficiency (PKLR Exon 5)

Clear

Pyruvate Kinase Deficiency (PKLR Exon 7 Labrador Variant)

Clear

Pyruvate Kinase Deficiency (PKLR Exon 7 Pug Variant)

Clear

Pyruvate Kinase Deficiency (PKLR Exon 7 Beagle Variant)

Clear

Pyruvate Kinase Deficiency (PKLR Exon 10)

Clear

Trapped Neutrophil Syndrome (VPS13B)

Clear

Ligneous Membranitis (PLG)

Clear

HORMONES

Congenital Hypothyroidism (TPO, Tenterfield Terrier Variant)

Clear

IMMUNE

Complement 3 (C3) deficiency (C3)

Clear

Severe Combined Immunodeficiency (PRKDC)

Clear

Severe Combined Immunodeficiency (RAG1)

Clear

X-linked Severe Combined Immunodeficiency (IL2RG Variant 1)

Clear

X-linked Severe Combined Immunodeficiency (IL2RG Variant 2)

Clear

EYES

Progressive Retinal Atrophy – rcd1 Rod-cone dysplasia, rcd1 (PDE6B Exon 21 Irish Setter Variant)

Clear

Progressive Retinal Atrophy Rod-cone dysplasia, rcd1a (PDE6B Exon 21 Sloughi Variant)

Clear

Progressive Retinal Atrophy – rcd3 Rod-cone dysplasia, rcd3 (PDE6A)

Clear

Progressive Retinal Atrophy – CNGA (CNGA1 Exon 9)

Clear

Progressive Retinal Atrophy – prcd Progressive rod-cone degeneration (PRCD Exon 1)

Clear

Progressive Retinal Atrophy (CNGB1)

Clear

Progressive Retinal Atrophy (SAG)

Clear

Golden Retriever Progressive Retinal Atrophy 1 (SLC4A3)

Clear

Golden Retriever Progressive Retinal Atrophy 2 (TTC8)

Clear

Progressive Retinal Atrophy – crd1 (PDE6B)

Clear

Progressive Retinal Atrophy – crd2 (IQCB1)

Clear

Progressive Retinal Atrophy – crd4/cord1 (RPGRIP1)

Clear

Collie Eye Anomaly, Choroidal Hypoplasia (NHEJ1)

Clear

Achromatopsia (CNGA3 Exon 7 German Shepherd Variant)

Clear

Achromatopsia (CNGA3 Exon 7 Labrador Retriever Variant)

Clear

Autosomal Dominant Progressive Retinal Atrophy (RHO)

Clear

Canine Multifocal Retinopathy cmr1 (BEST1 Exon 2)

Clear

Canine Multifocal Retinopathy cmr2 (BEST1 Exon 5)

Clear

Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 Deletion)

Clear

Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 SNP)

Clear

Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 9)

Clear

Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 17)

Clear

Glaucoma Primary Open Angle Glaucoma (ADAMTS17 Exon 11)

Clear

Glaucoma Primary Open Angle Glaucoma (ADAMTS17 Exon 2)

Clear

Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts (HSF4 Exon 9 Shepherd Variant)

Clear

Primary Lens Luxation (ADAMTS17)

Clear

Congenital stationary night blindness (RPE65)

Clear

Macular Corneal Dystrophy (MCD) (CHST6)

Clear

KIDNEY + BLADDER

2,8-Dihydroxyadenine (2,8-DHA) Urolithiasis (APRT)

Clear

Cystinuria Type I-A (SLC3A1)

Clear

Cystinuria Type II-A (SLC3A1)

Clear

Cystinuria Type I-A (SLC7A9)

Clear

Hyperuricosuria and Hyperuricemia or Urolithiasis (SLC2A9)

Clear

Polycystic Kidney Disease (PKD1)

Clear

Primary Hyperoxaluria (AGXT)

Clear

Protein Losing Nephropathy (NPHS1)

Clear

X-Linked Hereditary Nephropathy (Samoyed Variant 2) (COL4A5 Exon 35)

Clear

Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy (COL4A4 Exon 3)

Clear

MULTISYSTEM

Primary Ciliary Dyskinesia (CCDC39 Exon 3)

Clear

Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis (CKCSID), Dry Eye Curly Coat Syndrome (FAM83H Exon 5)

Clear

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Clear

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND) (FLCN Exon 7)

Clear

Canine Fucosidosis (FUCA1)

Clear

Glycogen Storage Disease Type II, Pompe’s Disease (GAA)

Clear

Glycogen Storage Disease Type Ia, Von Gierke Disease (G6PC)

Clear

Glycogen Storage Disease Type IIIa (GSD IIIa) (AGL)

Clear

Mucopolysaccharidosis Type I (IDUA)

Clear

Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 1)

Clear

Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 2)

Clear

Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 5)

Clear

Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 3)

Clear

Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Whippet and English Springer Spaniel Variant)

Clear

Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Wachtelhund Variant)

Clear

Lagotto Storage Disease (ATG4D)

Clear

Neuronal Ceroid Lipofuscinosis 1 (PPT1 Exon 8)

Clear

Neuronal Ceroid Lipofuscinosis 2 (TPP1 Exon 4)

Clear

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia – NCL-A (ARSG Exon 2)

Clear

Neuronal Ceroid Lipofuscinosis 1 (CLN5 Border Collie Variant)

Clear

Neuronal Ceroid Lipofuscinosis 6 (CLN6 Exon 7)

Clear

Neuronal Ceroid Lipofuscinosis 8 (CLN8 English Setter Variant)

Clear

Neuronal Ceroid Lipofuscinosis (MFSD8)

Clear

Neuronal Ceroid Lipofuscinosis (CLN8 Australian Shepherd Variant)

Clear

Neuronal Ceroid Lipofuscinosis 10 (CTSD Exon 5)

Clear

Neuronal Ceroid Lipofuscinosis (CLN5 Golden Retriever Variant)

Clear

Adult-Onset Neuronal Ceroid Lipofuscinosis (ATP13A2)

Clear

GM1 Gangliosidosis (GLB1 Exon 15 Shiba Inu Variant)

Clear

GM1 Gangliosidosis (GLB1 Exon 15 Alaskan Husky Variant)

Clear

GM1 Gangliosidosis (GLB1 Exon 2)

Clear

GM2 Gangliosidosis (HEXB, Poodle Variant)

Clear

GM2 Gangliosidosis (HEXA)

 Clear

 

Globoid Cell Leukodystrophy, Krabbe disease (GALC Exon 5)

Clear

OTHER SYSTEMS

Autosomal Recessive Amelogenesis Imperfecta (Italian Greyhound Variant)

Clear

Persistent Mullerian Duct Syndrome (AMHR2)

Clear

Deafness and Vestibular Syndrome of Dobermans (DVDob, DINGS)

Clear

Shar-Pei Autoinflammatory Disease (SPAID, Shar-Pei Fever) (MTBP)

Clear

BRAIN AND SPINAL CORD

Alaskan Husky Encephalopathy, Subacute Necrotizing Encephalomyelopathy (SLC19A3)

Clear

Alexander Disease (GFAP)

Clear

Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration (SPTBN2)

Clear

Cerebellar Ataxia, Progressive Early-Onset Cerebellar Ataxia (SEL1L)

Clear

Cerebellar Hypoplasia (VLDLR)

Clear

Spinocerebellar Ataxia, Late-Onset Ataxia (CAPN1)

Clear

Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10)

 Clear

 

Benign Familial Juvenile Epilepsy, Remitting Focal Epilepsy (LGI2)

Clear

Degenerative Myelopathy (SOD1A)

Clear

Fetal-Onset Neonatal Neuroaxonal Dystrophy (MFN2)

Clear

Hypomyelination and Tremors (FNIP2)

Clear

Shaking Puppy Syndrome, X-linked Generalized Tremor Syndrome (PLP)

Clear

L-2-Hydroxyglutaricaciduria (L2HGDH)

Clear

Neonatal Encephalopathy with Seizures (NEWS) (ATF2)

Clear

Polyneuropathy, NDRG1 Greyhound Variant (NDRG1 Exon 15)

Clear

Polyneuropathy, NDRG1 Malamute Variant (NDRG1 Exon 4)

Clear

Narcolepsy (HCRTR2 Intron 6)

Clear

Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 15)

Clear

Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 4)

Clear

Juvenile Laryngeal Paralysis and Polyneuropathy (RAB3GAP1)

Clear

Hereditary Sensory Autonomic Neuropathy (HSAN), Acral Mutilation Syndrome (GDNF-AS)

Clear

Juvenile-Onset Polyneuropathy, Leonberger Polyneuropathy 1 (LPN1, ARHGEF10)

Clear

Spongy Degeneration with Cerebellar Ataxia 1 (SDCA1), SeSAME/EAST (KCNJ10)

Clear

Spongy Degeneration with Cerebellar Ataxia 2 (SDCA2) (ATP1B2)

Clear

HEART

Dilated Cardiomyopathy (PDK4)

Clear

Long QT Syndrome (KCNQ1)

Clear

MUSCULAR

Muscular Dystrophy Cavalier King Charles Spaniel Variant 1

Clear

Muscular Dystrophy Muscular Dystrophy (DMD Pembroke Welsh Corgi Variant )

Clear

Muscular Dystrophy Muscular Dystrophy (DMD Golden Retriever Variant)

Clear

Centronuclear Myopathy (PTPLA)

Clear

Exercise-Induced Collapse (DNM1)

Clear

Inherited Myopathy of Great Danes (BIN1)

Clear

Myostatin Deficiency, Bully Whippet Syndrome (MSTN)

Clear

Myotonia Congenita (CLCN1 Exon 7)

Clear

Myotonia Congenita (CLCN1 Exon 23)

Clear

Myotubular Myopathy 1, X-linked Myotubular Myopathy (MTM1)

Clear

METABOLIC

Hypocatalasia, Acatalasemia (CAT)

Clear

Pyruvate Dehydrogenase Deficiency (PDP1)

Clear

Malignant Hyperthermia (RYR1)

Clear

GASTROINTESTINAL

Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 53)

Clear

Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 8)

Clear

NEUROMUSCULAR

Congenital Myasthenic Syndrome (CHAT)

Clear

Congenital Myasthenic Syndrome (COLQ)

Clear

Episodic Falling Syndrome (BCAN)

Clear

SKIN & CONNECTIVE TISSUES

 

 

Dystrophic Epidermolysis Bullosa (COL7A1)

Clear

Ectodermal Dysplasia, Skin Fragility Syndrome (PKP1)

Clear

Ichthyosis, Epidermolytic Hyperkeratosis (KRT10)

Clear

Ichthyosis (PNPLA1)

Clear

Ichthyosis (SLC27A4)

Clear

Ichthyosis (NIPAL4)

Clear

Focal Non-Epidermolytic Palmoplantar Keratoderma, Pachyonychia Congenita (KRT16)

Clear

Hereditary Footpad Hyperkeratosis (FAM83G)

Clear

Hereditary Nasal Parakeratosis (SUV39H2)

Clear

Musladin-Lueke Syndrome (ADAMTSL2)

Clear

SKELETAL

Cleft Lip and/or Cleft Palate (ADAMTS20)

Clear

Hereditary Vitamin D-Resistant Rickets (VDR)

Clear

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia (COL9A3, Labrador Retriever)

Clear

Osteogenesis Imperfecta, Brittle Bone Disease (COL1A2)

Clear

Osteogenesis Imperfecta, Brittle Bone Disease (SERPINH1)

Clear

Osteogenesis Imperfecta, Brittle Bone Disease (COL1A1)

Clear

Osteochondrodysplasia, Skeletal Dwarfism (SLC13A1)

Clear

Skeletal Dysplasia 2 (COL11A2)

Clear

Craniomandibular Osteopathy (CMO) (SLC37A2)

Clear

 

 

 

 

Traits + COI + Diversity

Coat Color
E Locus (Mask, Grizzle, Recessive Red) EE
K Locus (Dominant Black) kyky
A Locus (Agouti, Sable) atat
D Locus (Dilute, Blue, Fawn) DD
B Locus (Brown, Chocolate, Liver, Red, Dudley) BB
Saddle Tan II
Other Coat Traits
Furnishings / Improper Coat (RSPO2) II
Long Haircoat (FGF5) GG
Shedding (MC5R) TT

Curly Coat (KRT71)

CC

Hairlessness (FOXI3)

NN

Hairlessness (SGK3)

NN

Oculocutaneous Albinism Type 2 – OCA2, Doberman Z Factor Albinism (SLC45A2)

NN
OTHER BODY FEATURES
Brachycephaly (BMP3) CC
Natural Bobtail (T) CC
Hind Dewclaws (LMBR1) CC
Blue Eye Color NN
BODY SIZE
Body Size – IGF1 NN
Body Size – IGF1R GG
Body Size – STC2 TT
Body Size – GHR (E195K) GG
Body Size – GHR (P177L) CC
PERFORMANCE
Altitude Adaptation (EPAS1) GG
GENETIC DIVERSITY
Inbreeding Coefficient 43%
MHC Class II – DLA DRB1 No Diversity
MHC Class II – DLA DQA1 and DQB1 No Diversity

 

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